The 24-Hour Urinary Copper Test is a laboratory investigation used to measure the total amount of copper excreted through urine over a 24-hour period.
Copper is an essential trace mineral that supports iron metabolism, energy production, connective tissue formation and normal nervous system function. However, abnormal copper accumulation or excretion may be associated with certain medical conditions.
This test helps healthcare professionals evaluate copper metabolism, investigate suspected Wilson's disease and monitor copper-related disorders.
Total copper excretion over 24 hours
Abnormally high urinary copper levels
Copper metabolism abnormalities
Possible copper accumulation associated with Wilson's disease
Response to treatment in certain copper-related conditions
Sample Type: 24-Hour Urine
Collection Period: Complete 24-hour urine collection
Test Category: Laboratory – Clinical Biochemistry
Collection Container: Laboratory-approved trace-element collection container
Follow your healthcare provider's instructions regarding medications and supplements.
Inform your doctor if you are taking copper supplements or medications used to treat Wilson's disease.
Do not stop or change prescribed medications without medical advice.
Use only the laboratory-approved collection container to minimize contamination.
Follow the laboratory's specific storage and transportation instructions.
Day 1 – Morning: Empty your bladder into the toilet after waking up. Do not collect this first urine. Record the exact time.
During the Next 24 Hours: Collect all urine passed throughout the day and night in the designated laboratory container.
Day 2 – Morning: At exactly the same time as the previous day's starting time, collect your final urine sample.
Storage: Store the urine collection according to the laboratory's instructions.
Submission: Deliver the complete sample to the laboratory as instructed.
Wilson's Disease
Copper Metabolism Disorders
Copper Accumulation Disorders
Monitoring of Wilson's Disease Treatment
The 24-Hour Urinary Copper Test may be used alongside other investigations, such as serum copper, ceruloplasmin and liver-related assessments, when clinically indicated.
Urinary copper results alone cannot definitively diagnose or exclude Wilson's disease. Results should be interpreted by a qualified healthcare professional alongside symptoms, medical history and other investigations.
Please confirm test availability, collection container requirements and sample handling instructions with the laboratory before booking.
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