Anti Reticular Antibody

The Anti-Reticulin Antibody (ARA) Test is a blood test used to detect autoantibodies directed against reticulin-associated structures found in connective tissues of the body.

This test has historically been used to help healthcare professionals investigate Celiac Disease, an autoimmune condition in which consuming gluten triggers an immune reaction that can damage the lining of the small intestine.

Although Anti-Reticulin Antibody testing may provide additional information in selected cases, it has largely been replaced by more accurate celiac disease antibody tests.

What Does This Test Check?

• Detects anti-reticulin antibodies in the blood.

• May support the investigation of suspected Celiac Disease.

• Helps identify certain autoimmune antibody responses associated with gluten-related disorders.

• Provides additional diagnostic information alongside other celiac disease investigations.

• May assist in evaluating patients with symptoms such as chronic diarrhea, abdominal discomfort, bloating, and unexplained weight loss.

• Helps healthcare professionals determine whether further investigations are required.

Sample Requirements

• Sample Type: Serum

• Required Quantity: 2 cc (2 ml)

• Department: Immunology / Serology (subject to laboratory confirmation).

Patient Preparation

• Fasting is generally not required for the Anti-Reticulin Antibody Test.

• Continue consuming gluten before testing unless your doctor advises otherwise.

• Avoid starting a gluten-free diet before testing, as it may affect antibody levels and test results.

• Inform your healthcare provider if you have a history of Celiac Disease or other autoimmune disorders.

• Inform your doctor about any medications, supplements, or dietary restrictions you are currently following.

• Follow any specific sample collection instructions provided by the laboratory.

Important Information

The Anti-Reticulin Antibody Test is an older diagnostic in