Serum Pivka - Ii Level

The Serum PIVKA-II Level Test is a blood test used to measure PIVKA-II (Protein Induced by Vitamin K Absence or Antagonist-II), also known as Des-Gamma-Carboxy Prothrombin (DCP).

PIVKA-II is an abnormal form of prothrombin that may be elevated in certain liver conditions, including hepatocellular carcinoma (HCC). This test may be used by healthcare professionals as an additional marker during liver disease assessment and monitoring.

What Does This Test Check?

The test measures the level of PIVKA-II in the blood and may help with:

• Supporting the assessment of suspected hepatocellular carcinoma (HCC).

• Monitoring patients with known liver cancer.

• Evaluating changes in PIVKA-II levels during treatment.

• Providing additional information alongside other liver investigations and tumour markers.

Sample Requirements

• Sample Type: Serum

• Sample Quantity: To be confirmed by the laboratory.

• Collection Instructions: Blood should be collected in an appropriate tube, and serum should be separated according to laboratory requirements.

Patient Preparation

• Fasting is generally not required.

• Inform the healthcare professional about current medications, particularly vitamin K antagonists such as warfarin.

• Follow any specific preparation instructions provided by the laboratory.

Important Information

• Elevated PIVKA-II levels do not independently confirm liver cancer.

• Results should be interpreted alongside clinical findings, imaging, and other relevant investigations.

• Vitamin K deficiency, certain medications, and liver conditions may also affect PIVKA-II levels.

• This test should be used as part of a broader clinical assessment.

Reporting Time: To be confirmed by the laboratory.

Please confirm test availability and sample collection requirements with the laboratory before booking.