VMA

Product Description

The VMA (Vanillylmandelic Acid) Test is a laboratory investigation used to measure the amount of vanillylmandelic acid in urine collected over a 24-hour period.

VMA is a breakdown product of catecholamines, including adrenaline and noradrenaline. This test helps healthcare professionals evaluate catecholamine metabolism and investigate certain conditions associated with hormone-producing tumours, particularly pheochromocytoma and neuroblastoma.

What Does This Test Check?

• Vanillylmandelic Acid (VMA) levels in urine.

• Catecholamine breakdown and metabolism.

• Abnormal VMA excretion that may require further clinical investigation.

• Supporting evidence for certain catecholamine-producing tumours.

Sample Requirements

• Sample Type: 24-Hour Urine.

• Sample Quantity: Complete 24-hour urine collection.

• Collection Container: Laboratory-approved urine collection container.

• Preservative: As specified by the laboratory.

• Test Category: Laboratory – Biochemistry.

Patient Preparation

• Follow the laboratory's dietary instructions before and during sample collection.

• Certain foods, beverages, and medications may affect VMA results.

• Inform your healthcare professional about current medications and supplements.

• Do not stop or change prescribed medications without medical advice.

• Confirm the required collection container, preservative, and storage conditions before starting.

24-Hour Urine Collection Instructions

1. Day 1 – Morning: Empty your bladder into the toilet and record the exact time. Do not collect this first urine sample.

2. During the Next 24 Hours: Collect all urine passed during the day and night in the laboratory-provided container.

3. Day 2 – Morning: At the same time as the previous day's start time, collect the final urine sample and add it to the container.

4. Storage: Keep the collected urine under the storage conditions specified by the laboratory.

5. Submission: Deliver the complete collection to the laboratory promptly after the collection period.

Relevant Conditions

• Pheochromocytoma.

• Neuroblastoma.

• Certain catecholamine-related disorders.

Important Information

• Abnormal VMA levels do not independently confirm a specific tumour or medical condition.

• A normal VMA result does not completely exclude a catecholamine-producing tumour.

• Plasma free metanephrines or urinary fractionated metanephrines are generally preferred for the initial biochemical evaluation of suspected pheochromocytoma.

• Results should be interpreted by a qualified healthcare professional alongside symptoms and other investigations.

• Missing urine samples, incorrect storage, or failure to follow collection instructions may affect test accuracy.

Reporting Time

To be confirmed by the laboratory.

Please confirm test availability, dietary restrictions, preservatives, and sample collection requirements with the laboratory before booking.