Serum Anti-gbm

The Serum Anti-GBM Antibody Test is a blood test used to detect antibodies directed against the glomerular basement membrane (GBM), a specialised structure in the kidneys.

This test may help healthcare professionals investigate suspected anti-GBM disease, an autoimmune condition that can cause inflammation and damage to the kidneys and, in some cases, the lungs.

What Does This Test Check?

The test detects antibodies against the glomerular basement membrane and may assist in evaluating:

• Suspected anti-GBM disease.

• Goodpasture syndrome.

• Rapidly progressive glomerulonephritis.

• Certain autoimmune conditions affecting the kidneys and lungs.

Sample Requirements

• Sample Type: Serum

• Sample Quantity: To be confirmed by the laboratory.

• Collection Instructions: Blood should be collected in an appropriate tube, and serum should be separated according to laboratory requirements.

Patient Preparation

• Fasting is generally not required.

• Inform the healthcare professional about current medications and relevant medical history.

• Follow any specific preparation instructions provided by the laboratory.

Important Information

• A positive result may support the diagnosis of anti-GBM disease but should be interpreted alongside clinical findings and other investigations.

• A negative result does not completely exclude the condition.

• Additional tests, including kidney function tests, urinalysis, and sometimes kidney biopsy, may be required.

• Suspected anti-GBM disease requires prompt medical assessment because it can progress rapidly.

Reporting Time: To be confirmed by the laboratory.

Please confirm test availability and sample collection requirements with the laboratory before booking.